Plain-English translation of NCT06276634 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Multiple Sclerosis research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a treatment called Acute Intermittent Hypoxia (AIH)—brief sessions where you breathe air with reduced oxygen levels. Researchers believe this might help your brain rewire itself and improve movement and motor control in people with multiple sclerosis. The study will measure changes in how your brain works during movement tasks and test whether the treatment actually helps with motor function.
People with MS often have to work much harder than others to control movement because their brains recruit extra areas to compensate for MS-related damage. This trial exists to see whether this treatment might help your brain adapt and become more efficient at controlling movement, potentially reducing that extra effort.
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You will be randomly assigned to receive either the real treatment or a sham (inactive) version first. Each phase lasts 5 days, with a 2-week break in between, then you'll cross over to the other type. During each 5-day phase, you'll breathe special air mixtures while researchers monitor you. You'll also complete movement tasks and have brain imaging scans (MRI) before, during, and after each phase to measure any changes in how your brain controls movement.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States