Plain-English translation of NCT06280742 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Multiple Sclerosis research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
INFLANET is a research study that uses a special type of brain imaging called PET-MRI to look at inflammation in the brains of people with relapsing multiple sclerosis. This imaging uses a radioactive tracer called [18F]-DPA-714, which helps doctors see where inflammation is happening. The study compares brain scans from MS patients to healthy volunteers to better understand how the disease affects the brain.
Doctors know that inflammation in the brain is important in multiple sclerosis, but they don't have a clear way to see and measure it in living patients. This study aims to develop better imaging tools that could help doctors understand MS better and potentially predict how the disease will progress.
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If you're an MS patient, you'll visit the clinic twice: once for screening (which includes neurological exams and blood tests) and once for your brain imaging scan. If you're a healthy volunteer, you'll have two or three visits depending on which location you're at—the first for screening and one or two for brain imaging. The imaging itself involves lying still in an MRI machine while a radioactive tracer is injected to help visualize inflammation in your brain. The whole process takes a few hours.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
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