Regular MRI scans versus standard monitoring for slow-growing prostate cancer

This trial is testing whether adding regular MRI scans to the standard monitoring approach helps catch changes in slow-growing prostate cancer earlier and more accurately. Men with low- or medium-risk prostate cancer who have chosen active surveillance (close monitoring instead of immediate surgery or radiation) are randomly assigned to either receive regular MRI scans along with blood tests, or to follow the current standard care with blood tests and physical exams. The goal is to see if MRI scans can better detect when cancer is progressing, so treatment can be started at the right time.

When men choose active surveillance for slow-growing prostate cancer, doctors need reliable ways to know if the cancer is changing and needs treatment. Currently, doctors rely on blood tests and physical exams, but these methods miss some cancer changes or aren't always accurate. This trial exists to find out whether regular MRI scans—which give a clearer picture of the prostate—can improve monitoring and help catch progression earlier.