Plain-English translation of NCT06353620 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Epilepsy research guide →This study uses a specialized type of brain scan called high-density electroencephalography (HD-EEG) along with standard brain MRI scans to map how different parts of the brain communicate with each other. Researchers want to understand how epilepsy and two rare genetic conditions—Angelman syndrome and Dup15q syndrome—change the brain's wiring and function, and whether these changes improve after treatment.
Right now, doctors don't have good ways to predict which patients will respond to epilepsy treatment or to track whether rare genetic conditions are improving over time. This study aims to create reliable markers from brain imaging that could help doctors make better treatment decisions and monitor progress in people with these conditions.
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If you qualify, the study will use brain scans and EEG recordings you've already had done as part of your regular medical care—no new procedures are needed. You'll also be asked to complete a cognitive and behavioral evaluation (like memory and attention tests) to help researchers understand how your condition affects thinking and behavior. Researchers will then analyze all this information together to map your brain's connectivity patterns and see how they relate to your epilepsy or genetic syndrome.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
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