Plain-English translation of NCT06402357 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing High Intensity Focused Ultrasound (HIFU) as a treatment option for men whose prostate cancer has returned after radiation therapy. HIFU uses focused sound waves to heat and destroy cancer cells in a specific area of the prostate, rather than treating the entire gland. The goal is to see whether this targeted approach works well and causes fewer side effects than more extensive treatments.
Most information about HIFU for recurrent prostate cancer comes from older studies that didn't have access to the advanced imaging tools doctors use today. This trial aims to better understand whether this treatment works and is safe for men with recurrent disease using current diagnostic methods.
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If you join this trial, you would undergo the HIFU procedure, which involves inserting a small ultrasound probe through the rectum to deliver targeted heat to the cancer area. Your doctors will use imaging scans (MRI or PET scans) to guide the treatment precisely. You would be followed up to assess how well the treatment worked and whether you experience any side effects, with researchers tracking both your cancer outcomes and how the treatment affects your quality of life.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
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