Plain-English translation of NCT06423976 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →Researchers are collecting tumor tissue and analyzing gut bacteria from men with prostate cancer to understand how the bacteria in your intestines might affect how well cancer treatments work. Recent studies suggest that the types of bacteria living in your gut could play an important role in whether treatments like chemotherapy and immunotherapy are more or less effective.
Scientists have noticed in lab studies that the composition of gut bacteria seems to affect how well certain cancer treatments work. This trial aims to explore whether understanding and potentially modifying someone's gut bacteria could help improve treatment outcomes for men with prostate cancer.
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If you join this study, you will have a tumor biopsy performed (a procedure where doctors take a small sample of your tumor tissue using a needle or during surgery). This tissue sample will be sent to research laboratories where scientists will analyze it to look at the genetic makeup of your cancer and examine your gut bacteria. The study is observational, meaning researchers are collecting information and samples but not testing a new drug—they're trying to understand connections between your cancer biology and your microbiome.
AI-generated summary from trial data · Jun 30, 2026 · Not medical advice
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