Plain-English translation of NCT06428006 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Multiple Sclerosis research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether a type of therapy called cognitive behavioral therapy for insomnia (CBT-I) can help people with multiple sclerosis sleep better and reduce fatigue. CBT-I is a evidence-based approach that teaches specific strategies to improve sleep without relying on medication. The study will compare this therapy to an educational program focused on sleep and lifestyle habits.
Sleep problems affect up to 90% of people with multiple sclerosis and can make fatigue, pain, depression, and anxiety worse. Currently, there aren't many specialized treatments designed specifically for insomnia in people with MS, so this study aims to see if this therapy can help.
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You would attend six weekly one-on-one sessions over video conference, each lasting 45 to 60 minutes. Depending on which group you're randomly assigned to, you'll either receive cognitive behavioral therapy for insomnia (which teaches specific sleep-improvement strategies) or educational sessions about sleep and lifestyle. All sessions are conducted with a trained research assistant through a secure, private video connection.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
United States