Plain-English translation of NCT06545214 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand why some people with drug-resistant epilepsy—seizures that don't stop with medication—have serious breathing problems during and after seizures. This study will monitor your brain activity, breathing, and sleep patterns during a 24-hour hospital stay to see how seizures affect your respiratory system and how alert you are at different times.
About 30% of people with epilepsy have seizures that don't respond to medications, and they face a rare but serious risk called SUDEP (sudden unexpected death in epilepsy), which often happens during sleep after a seizure and involves breathing failure. By studying the connection between seizures, breathing problems, and sleep, researchers hope to better understand and eventually prevent these life-threatening events.
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You will stay in the hospital for 24 hours and undergo several monitoring procedures, all using equipment already used routinely in patient care. During your stay, doctors will record your brain activity, monitor your breathing continuously, perform an overnight sleep study, and conduct three breathing challenge tests (one while awake and two while sleeping), plus test your response to sounds. The entire visit is designed to give researchers a detailed picture of how your breathing and alertness respond to your seizures and sleep.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
France