Plain-English translation of NCT06575257 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing whether , a newer prostate cancer medication, works better than hormone therapy alone when given before prostate surgery in men with high-risk prostate cancer. You would receive either hormone injections plus pills, or hormone injections alone, for 12 weeks before having your prostate removed. The goal is to see if the medication combination shrinks tumors more effectively and leaves less cancer behind.
Doctors want to know if this newer medication can help reduce the amount of cancer remaining after surgery in men with aggressive prostate cancer, which could improve long-term outcomes.
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You would be randomly assigned to one of two groups. Both groups receive a hormone injection every 4 weeks for 12 weeks; one group also takes the new medication as a pill twice daily. During this 12-week period, you'll have imaging scans before and after treatment to monitor how well it's working. After 12 weeks, you'll have prostate surgery with lymph node removal. The study involves regular clinic visits to monitor your health and check blood work.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
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