Plain-English translation of NCT06655233 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Pancreatic Cancer research guide →Researchers are studying the bacteria and microbes that live inside pancreatic cancer tumors to understand whether they affect how quickly the cancer grows and how well patients respond to chemotherapy. This study uses a minimally invasive needle biopsy procedure to safely collect tiny tissue samples from the tumor, then analyzes what microorganisms are present. The goal is to learn whether certain microbes or their byproducts could help doctors predict outcomes and personalize treatment plans for pancreatic cancer patients.
Most pancreatic cancer patients are diagnosed when surgery is no longer possible, making it critical to find new ways to understand the disease and predict which treatments will work best. Recent research suggests that the bacteria living inside tumors may play a role in cancer growth and treatment response, but this has not been thoroughly studied in pancreatic cancer.
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If you qualify, you will undergo a minimally invasive needle biopsy procedure (called EUS-FNB) that your doctor may have already recommended as part of your cancer diagnosis. During this procedure, doctors will collect a small tissue sample from your tumor for analysis, and researchers will use the remaining tissue after routine testing to study the bacteria and microbes present. You will be followed over time so researchers can track how your cancer responds to treatment and whether the microbes found in your tumor relate to your prognosis.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
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