Plain-English translation of NCT06667232 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Epilepsy research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial compares four different ways of delivering electrical stimulation directly to the brain using electrodes that are already placed during epilepsy evaluation. Researchers want to understand which stimulation pattern works best at calming abnormal brain activity in people whose epilepsy doesn't respond to medication. The four patterns being tested range from single quick pulses to more complex burst patterns that mimic how the brain naturally works.
Many people with epilepsy don't respond well to standard medications, and doctors need better ways to control their seizures. This study explores whether different electrical stimulation patterns can more effectively calm the overactive brain circuits that cause seizures, potentially leading to a better treatment option for people with hard-to-treat epilepsy.
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Since you would already be in the hospital with brain electrodes in place for your epilepsy evaluation, researchers would use those same electrodes to deliver four different types of electrical stimulation patterns while monitoring your brain activity. You would receive these stimulations during rest periods and possibly after seizures occur, allowing doctors to see how each pattern affects your brain. The study doesn't require additional surgery or long-term commitment beyond your planned hospital stay.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
China
Sponsor
Xuanwu Hospital, Beijing
Enrollment target
~20 participants
Started
January 2025
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
14 Years – 65 Years
Last updated on clinicaltrials.gov in January 2025.
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Central contact
Liankun Ren, MD
Xuanwu Hospital, Beijing
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.