Plain-English translation of NCT06828328 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Pancreatic Cancer research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing a new treatment called , which uses your own immune cells that are removed from your tumor, genetically modified in a laboratory to work better against cancer, and then infused back into your body. The goal is to see if this approach is safe and whether it can help control pancreatic cancer that has stopped responding to standard chemotherapy or other treatments.
Pancreatic cancer is a serious disease, and many patients find that their tumors stop responding to standard treatments like chemotherapy. This trial exists because researchers believe that using engineered immune cells might offer a new option for patients who have exhausted conventional therapy.
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First, your tumor tissue will be removed and sent to a laboratory where scientists will extract immune cells, edit them genetically, and grow large numbers of them over several weeks. Once the cells are ready, you will receive medications to temporarily reduce your immune cell count, followed by an infusion of the engineered cells through an IV. You will then be closely monitored with blood tests and imaging scans to track how you respond and watch for any side effects.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
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