Adding chemotherapy to radiation therapy for aggressive prostate cancer

This trial is testing whether adding docetaxel chemotherapy after radiation therapy can help men with high-grade prostate cancer have better outcomes. Some men will receive standard radiation therapy alone, while others will receive radiation therapy followed by 4 to 6 rounds of this medication given through an IV. The goal is to see if the added chemotherapy helps prevent the cancer from coming back or spreading.

Aggressive prostate cancer can come back even after standard treatment with radiation or surgery. Researchers want to know if adding this medication after radiation therapy can improve survival and reduce the chances that the cancer will return.