Plain-English translation of NCT06974305 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Epilepsy research guide →Researchers want to better understand how epilepsy affects the brain by using three different imaging technologies together: a PET scan (which measures how much sugar the brain uses), an MRI scan (which shows blood flow), and an EEG test (which records electrical activity). By comparing these three types of scans in people with epilepsy and healthy volunteers, the research team hopes to learn more about the brain changes that happen between seizures.
There's a gap in understanding exactly how epilepsy affects the brain's metabolism and electrical activity. By combining multiple imaging methods at the same time, researchers hope to get a clearer picture of what's happening in the brains of people with epilepsy, which could eventually help improve diagnosis and treatment.
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If you qualify, you will come in for imaging visits where you'll complete three types of brain scans: a PET scan (which involves a small injection of radioactive tracer), an MRI scan (a magnetic imaging machine), and an EEG test (which uses electrodes on your scalp to record brain waves). The study compares people with epilepsy to healthy volunteers to see how the brain patterns differ between the two groups.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States
Sponsor
Massachusetts General Hospital
Enrollment target
~30 participants
Started
September 2023
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in April 2026.
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Central contact
Magdelena S Allen, BA
Massachusetts General Hospital
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