Plain-English translation of NCT07159789 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Multiple Sclerosis research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a treatment called repetitive transcranial magnetic stimulation (rTMS), which uses magnetic pulses to stimulate specific areas of the brain. The goal is to see if this non-invasive approach can help reduce leg stiffness and improve walking ability in people with multiple sclerosis. Researchers will measure changes in disability level, walking distance, and quality of life.
Many people with MS experience painful leg stiffness (spasticity) that limits their ability to walk and affects daily life. Current treatments don't work well for everyone, so researchers are exploring whether this medication might offer a new option to reduce these symptoms.
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If you enroll, you will receive either real magnetic brain stimulation or a sham (placebo) version using the same machine at very low intensity—neither you nor the researchers will know which you receive. You'll have sessions where magnetic pulses are applied to your scalp, and you'll complete walking tests and questionnaires about your symptoms and quality of life. The researchers will also use EEG (brain wave monitoring) to measure how your brain activity changes.
AI-generated summary from trial data · Aug 2, 2026 · Not medical advice
Canada
Sponsor
Clinique Neuro-Outaouais
Collaborators
University of Ottawa
Enrollment target
~60 participants
Started
October 2025
Primary completion
October 2027
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Francois Jacques, Neurologist
Clinique Neuro-Outaouais
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.