Recruiting

Testing walking and balance tests in people with multiple sclerosis

Plain-English translation of NCT07505355 on ClinicalTrials.gov ↗ · Source last updated April 2026 · Translation generated June 2026 ·

What is this trial?

This study is testing two new walking tests—the Walking Adaptability Ladder Test and the Foot Tap Test—to see if they are reliable and accurate ways to measure how well people with multiple sclerosis can walk and stay balanced. Researchers want to understand if these tests give consistent results and whether they can accurately detect changes in walking ability.

Currently, doctors use several different tests to measure walking and balance in multiple sclerosis, but some of these tests may not be sensitive enough to catch small but important changes in a person's ability. This study aims to develop and validate better measurement tools so that doctors and researchers can more accurately track how the disease affects movement.

Do you qualify?

You likely qualify if…

you have been diagnosed with definite multiple sclerosis according to established diagnostic criteria
you have been relapse-free for at least 30 days before joining
your disability level is mild, with an EDSS score between 0 and 3.5
you are able to understand and complete the study tests and questionnaires without significant cognitive difficulties
you are age and sex-matched if you are in the healthy control group (within a 5-year age range)

You likely don't qualify if…

you have been diagnosed with another neurological disease besides multiple sclerosis
you have significant cognitive decline that would prevent you from completing tests and questionnaires
you have other neurological, orthopedic, or vision problems that would affect your ability to walk safely
you have had a recent relapse or are currently in a relapse period

What participation looks like

If you join, you will complete several walking and balance tests during visits at a hospital or university clinic in Spain, Italy, or Belgium. You will do tests like walking a set distance, stepping in place, rising on your heels, and maintaining your balance—some tests will be repeated one week later to check if results are consistent. You will also complete questionnaires about your walking ability, fatigue, balance confidence, and any falls you may have experienced.

Testing walking and balance tests in people with multiple sclerosis

What is this trial?

Do you qualify?

What participation looks like

Trial locations(4 sites)