Recruiting

Special MRI Scan to Screen for Pancreas Cancer in High-Risk People

Plain-English translation of NCT07612046 on ClinicalTrials.gov ↗ · Source last updated July 2026 · Translation generated July 2026 · How we translate trials

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What is this trial?

This pilot study is developing a dedicated MRI scan of the pancreas to help find pancreatic cancer earlier in people who have a high risk for developing it. Researchers want to see if this specialized imaging can detect cancer better than standard scans. You would have an MRI scan and an ultrasound procedure as part of your regular cancer screening appointments.

Pancreatic cancer is often found at a late stage when it's harder to treat. People with a family history or certain genetic mutations have a much higher risk of developing this disease. This study aims to create better screening tools to catch pancreatic cancer as early as possible in these high-risk patients.

Do you qualify?

You likely qualify if…

you have two close family members (parents, siblings, or children) with pancreatic cancer, or you carry a genetic mutation known to increase pancreatic cancer risk with a close relative who has had the disease
you are at least 21 years old, and ideally around age 50 or 10 years younger than the youngest family member diagnosed with pancreatic cancer
you are already part of the Memorial Sloan Kettering Pancreatic Tumor Registry and have had an MRI scan within the last 3 years with no concerning findings
you live in the United States and are willing to be contacted for follow-up appointments
you are scheduled for an endoscopic ultrasound as part of your regular cancer screening

You likely don't qualify if…

you have any metallic implants or devices that are unsafe for MRI scans
you have a history of claustrophobia or have needed anxiety medication during previous MRI scans
you have had abdominal surgery that might make it difficult to interpret imaging or ultrasound results
you have medical conditions that would make it unsafe for you to receive anesthesia during the ultrasound procedure

What participation looks like

If you join this study, you would complete a dedicated MRI scan of your pancreas as part of your regular cancer screening visits. On the same day, you would also have an endoscopic ultrasound (a procedure where a tiny camera is guided down your throat to get detailed images of the pancreas). The study team will ask you to consent to follow-up contact so they can track how well this new scanning method works over time.

AI-generated summary from trial data · Jul 21, 2026 · Not medical advice

Trial locations(7 sites)

United States

Memorial Sloan Kettering Basking Ridge (Consent Only), Basking Ridge, New Jersey

Memorial Sloan Kettering Monmouth (Consent only), Middletown, New Jersey

Memorial Sloan Kettering Bergen (Consent Only), Montvale, New Jersey

Memorial Sloan Kettering Suffolk-Commack (Consent only), Commack, New York

Memorial Sloan Kettering Westchester (Consent only), Harrison, New York